Description
MOTS-c (Human) – Research Grade
Product Overview
MOTS-c is a mitochondrial-derived peptide composed of 16 amino acids with the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg. Unlike nuclear-encoded peptides, MOTS-c is encoded within the mitochondrial 12S rRNA gene. In research settings, scientists study MOTS-c for its role in cellular metabolism, AMPK activation, and mitochondrial signaling pathways.
First identified in 2015, MOTS-c has become a subject of interest in metabolic and aging research. In addition, it is studied for its involvement in mitochondrial-nuclear communication and cellular stress adaptation.
When researchers buy MOTS-c peptide, they look for proven purity, full lab reports, and quick USA shipping. Johnson Peptide delivers all three. Therefore, if you search for MOTS-c for your lab work, you have come to the right place.
Key Research Applications
Researchers who study MOTS-c peptide use it in several laboratory settings:
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Mitochondrial Signaling Research: Scientists study MOTS-c’s role in mitochondrial-nuclear communication and retrograde signaling pathways.
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Metabolic Studies: Researchers examine MOTS-c’s effects on AMPK activation, glucose metabolism, and energy homeostasis in controlled models.
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Aging Research: MOTS-c is used to investigate cellular stress resistance, mitochondrial function, and metabolic adaptation in aging models.
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Cellular Energy Regulation: Scientists study MOTS-c’s involvement in ATP production, oxidative stress response, and mitochondrial biogenesis.
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Comparative Studies: MOTS-c is compared against other mitochondrial-derived peptides to understand functional differences.
For related research, MOTS-c is often studied alongside other metabolic and mitochondrial signaling compounds.
Product Specifications
| Specification | Detail |
|---|---|
| Peptide Type | Mitochondrial-Derived Peptide |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Formula | C₁₀₁H₁₅₈N₃₂O₂₀ |
| Molecular Weight | Approximately 2176.6 g/mol |
| CAS Number | 1627580-64-6 |
| Purity | ≥99% (HPLC verified, third-party tested) |
| Form | Lyophilized (freeze-dried) powder |
| Storage | Store at -20°C. Protect from light and moisture. |
| Source | Synthetic Human Sequence |
Available Strengths
| Strength | Catalog Code | Best For |
|---|---|---|
| 10mg | JP-MOTSC-10 | Small-scale in vitro screening |
| 20mg | JP-MOTSC-20 | Standard research protocols |
| 40mg | JP-MOTSC-40 | Extended study series and high-volume research |
Why Choose MOTS-c for Research?
| Feature | Benefit for Your Research |
|---|---|
| Mitochondrial-Encoded | Allows study of mitochondrial-nuclear communication pathways |
| AMPK Activation | Provides a model for studying energy regulation and metabolic signaling |
| 16-Amino Acid Sequence | Well-characterized peptide with published research |
| ≥99% Purity | Reduces experimental variables for reproducible results |
Quality Assurance
When you buy MOTS-c peptide from Johnson Peptide, you get:
| Quality Step | What This Means for Your Work |
|---|---|
| HPLC Check | Confirms ≥99% purity, so your tests have fewer unknowns |
| Mass Spectrometry | Validates molecular weight and peptide identity |
| Outside Lab Test | A second lab checks our work for fair results |
| Certificate of Analysis | Full records for each batch we ship |
| Trackable Batch | Each vial links to its own lab report |
As a result, you can trust your supplies stay the same from batch to batch. This matters a lot for getting results you can repeat.
View our Certificate of Analysis library for batch-specific documentation.
How to Store, Mix, and Handle (For Lab Use)
Good handling keeps your peptide stable for your tests:
Storage (Before Mixing)
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Keep at -20°C (freezer)
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Shield from light (use dark vials or foil)
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Shield from wetness (keep drying packs nearby)
How to Mix
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Use sterile bacteriostatic water or sterile saline
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Swirl gently—do not shake hard
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Measure based on your test needs
Storage (After Mixing)
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Keep cold at 2-8°C
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Use within 14 to 30 days based on your plan
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Do not freeze and thaw more than once (split into small doses first)
Frequently Asked Questions
Q: What is MOTS-c peptide?
A: MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene. It is composed of 16 amino acids and is used in research for mitochondrial signaling and metabolic studies.
Q: What is the amino acid sequence of MOTS-c?
A: The sequence is Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg.
Q: What is the molecular weight of MOTS-c?
A: The molecular weight of MOTS-c is approximately 2176.6 g/mol.
Why Choose Johnson Peptide for MOTS-c?
| Feature | What You Get |
|---|---|
| ≥99% Purity | Outside labs check every batch |
| Certificate of Analysis | Full documentation with each order |
| USA Shipping | Fast, trackable delivery across the US |
| Research-Use Only | Clear compliance labeling |
| Expert Support | Our team answers lab questions |
Related Research Products
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CJC-1295 + Ipamorelin Blend → – Growth hormone research compounds
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Ipamorelin → – Selective ghrelin receptor agonist
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Research Peptides Collection → – Browse all our research compounds
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Certificate of Analysis Library → – View batch-specific documentation
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Contact Us → – Questions about MOTS-c or other peptides?
Ready to Order?
Ready to buy MOTS-c peptide for your lab work? Select your strength above (10mg, 20mg, or 40mg) and add to cart. Every order comes with a Certificate of Analysis and ≥99% purity verification.
Have questions before you buy? Contact us
⚠️ Important Note: All Johnson Peptide products are for laboratory research only. None of our products are for human or animal use, health treatment, or disease care. By purchasing, you confirm you are a trained researcher at least 21 years old. View our Privacy Policy for more information.
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